In 2000, Michele got married to Mark Vandersall. At the end of 2005, she welcomed her first child.
In 1988, Michele graduated from the University of California, Berkeley with a Bachelor of Arts in mass communications. She then joined the University of Southern California and finally earned her Master’s degree in 1991. She began her professional career at KFAN-AM as a host and reporter. She also served at WAQS-AM for a few years and then she earned the title of the first female analyst to call UNC-Charlotte men's basketball games. She began serving as the reporter and host of CBS Sports Spectacular in 1994.