Byrne finished his schooling at Balmain Public School and Hunters Hill High School. After that, she moved to Bradfield College in Crows Nest. Later, she joined Australian Theatre for Young People, where she started taking acting classes. After that, she moved at the University of Sydney. She studied acting at the Atlantic Theater Company in 1999.
Byrne made her acting debut in an Australian movie Dallas Doll, which was directed by Ann Turner. After a year, she appeared in an Australian soap opera Echo Point, which was directed by Helen Gaynor. The co-stars of this series are Jessica Napier, Melissa Tkautz, Liddy Clark, and John Clayton.
After some years, Byrne appeared in an American epic space opera Star Wars: Episode II – Attack of the Clones, which was directed by George Lucas. The co-stars of this movie are Ewan McGregor, Natalie Portman, Ian McDiarmid, and Samuel L. Jackson. The movie became a huge hit and made a collection of $649.4 million at the box office against the budget of $115 million.
Recently, Byrne appeared in a live-action/computer-animated comedy movie Peter Rabbit, which is directed by Will Gluck. The cast members of this movie are Domhnall Gleeson, Sam Neill, Daisy Ridley, Elizabeth Debicki, and Margot Robbie. The film became a 10th highest grossing movie of 2018 and grossed $229.5 million at the box office against the budget of $50 million.
So far, Byrne has appeared in numerous movies including My Mother Frank, I Capture the Castle, Take Away, The Tenants, The Dead Girl, 28 Weeks Later, The Tender Hook, I Love You Too, Adult Beginners, This Is Where I Leave You, Neighbors 2: Sorority Rising, I Love You, Daddy, and Juliet, Naked.
Likewise, Byrne has also appeared in numerous television series including, Fallen Angels, Wildside, Big Sky, Heartbreak High, Murder Call, Casanova, Portlandia, Hollywood Game Night, Last Week Tonight with John Oliver, No Activity, and The Immortal Life of Henrietta Lacks.
Byrne is an Australian by nationality and belongs to white ethnicity. Currently, she is in a romantic relationship with Bobby Cannavale, an American actor. The couple is blessed with two children. Their first child Rocco was born in 2016, and Rafa was born in November 2017. She has a pretty good relationship with her boyfriend and there no signs of conflict in their relationship.
Byrne has not married her husband yet. Previously, she had an affair with her boyfriend Brendan Cowell, an Australian writer, director, and actor.
Byrne earns a huge amount of money from her professional acting career. She has appeared in numerous movies and television series from which she must have collected a decent amount of salary. According to some source, her current net worth is estimated to be $16 million.
